Custom Lentiviral Particles

We offer a variety of high-quality, custom lentiviral particle services on demand. Options include lentivirus packaged with custom shRNA, miRNA, sgRNA, or ORF cDNA constructs, or with custom reporter constructs for transcription factor (TF) response elements or gene promoters. All custom lentivirus services are prompt, accurate and cost-effective. The lentiviral particles are ultra-purified to ensure the highest quality suitable for in vitro or in vivo applications. We also offer custom AAV and retroviral particles. Browse the service guide and various vector options below. To place an order or request more information, simply contact us

Advantages of LipExoGen Custom Lentivirus Services

  • Wide variety of lentiviral vectors to choose from. Click here to see our general vectors list.
  • Easily establish stable cell lines expressing shRNA against your gene of interest
  • Recruit shRNAs/miRNAs of interest into exosomes 
  • Validated shRNAs – we confirm the shRNA can provide at least 70% knockdown of your gene of interest using our superior fluorescence-based assay
  • Ultra-purified – all custom lentiviral particles are purified by PEG precipitation and sucrose-gradient centrifugation
  • Detect transduced cells in vivo with luciferase 
  • Easily study gene regulation with our innovative bright fluorescent (GFP, RFP) reporter constructs
  • Fast turnaround – usually 10-15 business days
  • Best value – take advantage of our optimized vectors and high-quality service for similar or reduced prices vs our competitors

Vector Options

Premade Vectors 

Fastest turnaround. Select the name of the destination vector you’re interested in on your form submission. View Premade Vectors List

General Vectors

We have a variety of general vectors that can be customized based on your needs. To request cloning or viral particle services using a customized version of one of our general vectors, please contact us.

View General Vectors List

Service Guide

*Based on 24-well format, 1-3×10^5 cells/well reaction size and 1:1 transfection ratio. @At least one construct in the mixture guaranteed to provide 70% or more knockdown efficiency as a standalone product. Additional constructs in the mixture are not validated, but sequence-predicted based on the same method used to generate validated constructs. Knockdown validation data not provided for shRNA mixtures.  ***Typical titer shown. Actual titers may vary depending on the size of the insert. #Starting price and turnaround shown for cloned DNA fragments less than 1.0 kb, without added sequences (such as enhancer or repressor sequences) and not having difficult secondary structure. ##Volumes and titers listed are estimates based on typical amounts. Actual amounts may vary.

Please note: Custom lentiviral particles are suitable for transduction of human or mouse cells. All products and services are for preclinical research use only and not intended for any therapeutic or diagnostic use. For more information, please see our Terms and Conditions.

Validated shRNA Lentiviral Particles

Starting price: $595

We provide high-titer custom lentiviral particles producing shRNAs for knockdown of your gene of interest in mammalian systems. We guarantee the clone you receive will have at least 70% knockdown efficiency because we validate the clones using a specific fluorescence-based reporter assay that is more reliable than standard qPCR. You don’t have to know any shRNA sequences at all to get started – simply tell us the gene accession number of the gene you want to knock down, and select one of our high-quality, new-version lentiviral vectors

Our lentiviral particles can allow for the easy establishment of stable cell lines expressing shRNA. If desired, we can provide lentiviral particles engineered to recruit shRNA to exosomes. 

After your order is confirmed, you can expect your custom lentivirus to be shipped out in about 10 business days. Knockdown validation data are also included as determined by our unique fluorescence microscopy assay. 

To view our catalog of pre-made validated shRNA lentivirus,  click here.

Custom miRNA Lentivirus

Starting price: $595

We provide high-titer custom lentiviral particles for expression of the stem-loop or mature miRNA of your choice. We guarantee the clone you receive is functional for the expression of the mature miRNA you specified. Our lentiviral particles can also allow you to easily establish stable cell lines expressing miRNA and recruiting miRNA to exosomes.

Simply tell us the gene accession number of the miRNA, and select one of our high-quality, new-version lentiviral vectors. After your order is confirmed, you can expect your custom lentivirus to be shipped out in about 10 business days.

Custom cDNA ORF Lentivirus

Starting price: $595

We provide high-titer custom lentiviral particles for expression of your specified ORF cDNA fragment. We guarantee the clone you receive is functional for the expression of the cDNA you specified. 

Simply tell us the gene accession number of the ORF cDNA fragment, and select one of our high-quality, new-version lentiviral vectors. After your order is confirmed, you can expect your custom lentivirus to be shipped out in about 10 business days.

Custom LentiCRISPR sgRNA Lentivirus

Starting price: $695

This is a fast and easy service which allows you to obtain high titer lentiviral particles customizable for CRISPR/Cas9 knockout of your gene of interest. 

To begin, just enter the gene accession number for the gene you want to knock-out.

After your order is confirmed, you can expect your custom lentivirus to be shipped out in about 10 business days. 

Custom TF Reporter Lentivirus

Starting price: $595

Take your gene regulation research to a new level with custom high titer lentiviral particles for mammalian expression of a fluorescent/bioluminescent reporter system responsive to your transcription factor (TF) of interest. We guarantee a functional reporter construct that is responsive to your TF of interest. Simply tell us the gene accession number for the TF, select one of our high-quality new-version lentiviral vectors and, if known, provide sequences of the TF response elements or the short DNA range or DNA elements the TF binds to. 

After your order is confirmed, you can expect your custom lentivirus to be shipped out in about 10 business days. As a part of our quality control process, we’ll also provide fluorescence microscopy images demonstrating the reporter activity. 

To view our catalog of pre-made lentiviral reporters for TFs/signal pathways, click here

Custom Gene Promoter Lentivirus

Starting price: $595*

Take your gene regulation research to a new level with custom lentiviral particles for mammalian expression of a fluorescent/bioluminescent reporter system driven by the human or mouse proximal promoter of your choice. This service also lets you add enhancer/repressor sequences to the proximal promoter if desired. 

Simply tell us the gene accession number for the gene controlled by the promoter you wish to clone, the sequence of the promoter DNA fragment, any details if adding additional regulatory elements, and select one of our high-quality new-version lentiviral vectors. After placing your order, you can expect to receive your custom lentiviral particles in as fast as 10 business days.

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