Custom Liposome Synthesis

Liposomes and Lipid Nanoparticles (LNPs)

We synthesize a wide variety of custom liposomes and LNPs for our customers. Whether you’re seeking regular plain or PEGylated liposomes, or complex formulations with small molecule inhibitors, dyes, and more, our team of liposome experts is ready to tackle your project with the dedication and accuracy you deserve. We also engineer custom LNPs for delivery of nucleic acids such as mRNA, siRNA, and sgRNA.

Here are just a few of the things that we do:

  • Lipid Nanoparticles (LNPs) for delivery of nucleic acid (mRNA, siRNA, CRISPR/Cas9, etc.)
  • Hydrophobic small molecule liposome formulation
  • Antibody/protein conjugation to surface of liposomes and LNPs
  • Conjugation of targeting moieties (e.g. Folate-targeted, cRGD, etc.)
  • Load multiple small molecules in one liposome construct (e.g. doxorubicin plus your inhibitor)
  • Fluorescent liposomes for in vivo imaging or detection of cellular uptake by flow cytometry, etc.
  • Synthesize panel of fluorescent liposomes with different sizes using various dyes
  • Liposomes with customer-defined gradients (pH, salt, EDTA, metal ion, etc.)
  • Immunologically active liposomes (co-formulation with adjuvants, conjugation of peptide antigen)
  • Custom cationic liposomes 
  • Synthesize regular plain or PEGylated liposome according to customer’s specifications for lipids, lipid ratio, liposome size, buffer, etc.

Drug Formulation Services

A more personalized service that allows you to incorporate drugs, small molecule inhibitors/activators, fluorescent dyes, peptides, and other molecules into liposomes to meet your research objectives. 

LNPs are the ideal platform for delivery of nucleotide cargo in vitro or in vivo. Customize your own LNPs with surface ligands and encapsulate your desired mRNA, sgRNA, siRNA, etc. 

Fast and efficient service that allows you to order custom-made liposomes online and have them delivered to your door. The online request form lets you customize lipid composition & mol%, lipid concentration, buffers & pH (internal/external), mean particle size, and volume.

Convenient service that allows you to modify our plain liposomes by referencing the product SKU and customizing the changes you want. 

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Featured Liposome Products

Designed to let you boldly enter new fields, our services spark innovation and drive your discoveries towards commercialization.